The 14th International Congress on Systemic Lupus Erythematosus (LUPUS 2021) together will 6th International Congress on Controversies in Rheumatology and Autoimmunity (CORA) will showcase the very best clinical, biological, and translational advances in the field of SLE and autoimmunity. At the joint congress we will highlight advances and insights from recent Systemic Lupus Erythematosus (SLE) research into the causes and outcomes of SLE, explore the promise of implementing a personalized approach to diagnosis, prognosis, and treatment, and provide a forum to hear exciting and innovative research from a new generation of investigators. The Congress will include an exceptional program focusing on the nexus between laboratory science and clinical translation, include multidisciplinary sessions on topics from B cells to nephritis, and offer a unique opportunity for the presentation of original data.